Talk with your doctor For those who have any questions about taking codeine or regarding how this medicine may possibly affect your newborn.
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It also can treat allergic skin reactions, offer sedation in clients undergoing surgical procedures, and take care of motion sickness. Codeine is often a narcotic (opioid) drug and may be habit-forming with long-time period use. To scale back your danger of dependancy or overdose, choose promethazine with codeine on the dosage and duration encouraged by your physician.
Certain medicines should not be made use of at or within the time of ingesting food items or ingesting certain forms of food items considering the fact that interactions may possibly happen.
olanzapine/samidorphan decreases effects of codeine by pharmacodynamic antagonism. Contraindicated. Samidorphan elicits opioid antagonistic effects and will increase chance of precipitating acute opioid withdrawal in clients dependent on opioids.
In case you have been getting promethazine/codeine frequently, usually do not halt using the medicine without speaking with your healthcare provider. Stopping way too rapidly could trigger severe Unwanted effects. Contact your Health care supplier immediately When you've got any of the subsequent signs or symptoms.
Warning ought to be exercised when promethazine hydrochloride and codeine phosphate syrup is administered to some nursing female.
Reserve concomitant prescribing of these medicines in patients for whom other treatment options are insufficient. Limit dosages and durations into the minimum demanded. Watch closely for indications of respiratory depression and sedation.
This could come about Even though you are having the medicine on the prescribed doses. There exists also a possibility of opioid overdose and Dying. To lower your danger, get promethazine with codeine at the dosage and duration suggested by your health practitioner.
valproic acid and codeine both equally enhance sedation. Steer clear of or Use Alternate Drug. Limit use to individuals for whom alternative cure selections are inadequate
clozapine decreases effects of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Warning/Monitor. Helps prevent conversion of codeine to its Lively metabolite morphine.
buprenorphine, extended-acting injection and codeine both of those maximize sedation. Prevent or Use Alternate Drug. Restrict use to individuals for whom alternative treatment solutions are inadequate
Making use of this drugs with any of the subsequent medicines just isn't encouraged. Your doctor may decide not to take care of you with this medication or transform many of the other medicines you're taking.
codeine will reduce the extent or outcome of prasugrel by inhibition of GI absorption. Applies only to oral method of both of those brokers. Prevent or Use Alternate Drug. Co-administration of opioid agonists delay and decrease absorption of prasugrel and its active metabolite presumably by slowing gastric emptying; consider the usage of a parenteral anti-platelet agent in acute coronary syndrome clients necessitating actavis promethazine and codeine co-administration of opioid agonists